Bullous pemphigoid
AUTOIMMUNE DISEASE OF SKIN AND CONNECTIVE TISSUE CHARACTERIZED BY LARGE BLISTERS
Pemphigoid, bullous; Bullous Pemphigoid; Bullous pemphigoid versus
Bullous pemphigoid (type of pemphigoid) is an autoimmune pruritic skin disease which typically occurs in people aged over 60, that may involve the formation of blisters (bullae) in the space between the epidermal and dermal skin layers. It is classified as a type II hypersensitivity reaction, which involves formation of anti-hemidesmosome antibodies, causing a loss of keratinocytes to basement membrane adhesion.